Monday 7 August 2017

Relationship between Finnish diabetes risk score and metabolic syndrome, Vitamin d and insulin resistance in women

metabolic syndrome journal articles
The Finnish Diabetes Risk Score (FINDRISC) is thought to be associated with Cardiovascular risk factors separately from type 2 diabetes. We aimed to evaluate the relationship between FINDRISC and metabolic syndrome, vitamin D and insulin resistance in this study.

115 women were recruited to study. Patients were divided into 5 groups according to FINDRISC score. Metabolic syndrome was assessed in patients with FINDRISC scores, body mass index (BMI), fasting blood glucose (FBG), HbA1c, insulin resistance index (HOMA-IR), high density lipoprotein cholesterol (HDL), triglyceride (TG), systolic and diastolic hypertension.

Monday 31 July 2017

Relationship between Finnish diabetes risk score and metabolic syndrome, vitamin d and insulin resistance in women

The  Finnish  Diabetes  Risk  Score  (FINDRISC)  is  thought  to  be  associated  with cardiovascular  risk  factors  separately  from  type  2  diabetes.  We  aimed  to  evaluate  the  relationship between FINDRISC and metabolic syndrome, vitamin D and insulin resistance in this study.

journal pathology clinical research115  women  were  recruited  to  study.  Patients  were  divided  into  5  groups  according  to FINDRISC score. Metabolic syndrome was assessed in patients with FINDRISC scores, body mass index (BMI), fasting blood glucose (FBG), HbA1c, insulin resistance index (HOMA-IR), high density lipoprotein cholesterol (HDL), triglyceride (TG), systolic and diastolic hypertension.


Monday 17 July 2017

Relationship between Finnish diabetes risk score and metabolic syndrome, vitamin d and insulin resistance in women


journal pathology clinical research
Metabolic syndrome (MS) is one of the most important causes leading to atherosclerotic vascular diseases and type 2 diabetes (Type 2 DM). The main components of metabolic syndrome are abdominal obesity, insulin resistance, increased blood pressure and lipid disorders. The frequency of the metabolic syndrome varies with increasing age and body weight, as well as with communities examined at the same time. In the United States, the incidence of metabolic syndrome is 27%, and the incidence of metabolic syndrome is increasing faster in women. In Turkey, the prevalence of metabolic syndrome is 38%. Metabolic syndrome is a combination of metabolic risk factors for cardiovascular diseases as well as insulin resistance. Recently, a simple, fast, non-invasive and practical screening tool has been developed to describe the high risk of future type 2 diabetes development in individuals.

Monday 10 July 2017

Do actual medical literature depict a satisfactory view of Left ventricular assistant device and Right ventricular failure?


cardiology journal impact factor
Incidence and prevalence of heart failure are rising up. In patients with advanced heart failure (AHF), Left Ventricular (LV) assist devices (LVADs) are an increasingly common therapy for AHF. Right ventricular failure (RVF) and device related issues make this therapy a challenge to apply to a broader population. On the other hand, RVF, after LVAD implantation, is associated with an increased incidence of perioperative mortality, prolonged length of stay and worst survival. Waiting for a randomized multicentre study, we just have to rely on clinical judgment of multidisciplinary experts, so the main goal of this review is to find out the relationship among LVAD and RVF.

Monday 3 July 2017

Adult-onset cerebral adrenoleukodystrophy with history of head trauma and neurosyphilis


X-linked adrenoleukodystrophy (X-ALD), an inherited peroxisomal disorder caused by mutations in the ABCD1 gene, has a highly variable clinical presentation. The two major phenotypes are cerebral ALD, marked by childhood onset inflammatory cerebral demyelination that is usually lethal, and adrenomyeloneuropathy (AMN), which typically manifests in adulthood as a non-inflammatory distal axonopathy that progresses to spastic paraplegia.

pathology and disease biology impact factor
Despite being a mono genetic condition, no simple genotype-phenotype correlation has been established; this suggests that additional environmental factors may influence the onset and progression of symptoms. Reports have suggested that head trauma may initiate the onset of the rapidly progressive inflammatory demyelination phenotype in previously asymptomatic patients with X-ALD. We report a case of adult-onset cerebral ALD in a patient with a remote history of traumatic brain injury and a recent history of neurosyphilis.

Friday 23 June 2017

Profile of Pterygium Cases Seen at a Tertiary Referral Hospital in The Philippines


ophthalmology case reports journal
Pterygium is a wing-shaped, fibrovascular degeneration of the bulbar conjunctiva that grows toward and over the cornea. It may cause irregular astigmatism, visual impairment, irritation, and cosmetic problems. Dryness, inflammation, and exposure to wind and dust or other irritants may be risk factors for its development but its pathogenesis is most strongly correlated with ultraviolet exposure making it more common in tropical countries near the equator (Agahan, 2010., Al-Bdour, 2004., Cajucom Uy, 2010., Chen, 2015., Droutsas, 2010., Essuman, 2014., Fernandes, 2005). It has also been reported several times that increasing age, male gender, outdoor occupation, and systemic factors like hypertension are risk factors suggesting a multifactorial etiology for this condition (Gris, 2000., Küçükerdönmez, 2007., Kurna, 2013). In a systematic review and meta-analysis done by Liu et al which included 20 countries, the geographic pooled prevalence rate of pterygium was around 10% in the general population (Essuman, 2014).

Thursday 15 June 2017

A case of heavy chain deposition disease complicated by acquired angioedema

pathology and disease biology journal
Heavy Chain Deposition Disease (HCDD) is rare, and presents with renal failure, proteinuria, hematuria, hypertension, and often hypocomplementemia. HCDD may mimic the pathology of immune complex, crescentic glomerulonephritis, with isolated heavy chain deposits along mesangial, glomerular, and tubular Basement Membranes (BMs), without associated light chains. The predominant heavy chain subtype is gamma. Rare cases of alpha and mu subtypes have also been reported. Immunofluorescence for heavy chains alone is diagnostic. Renal pathology includes mesangial matrix expansion, hypercellularity, and nodular sclerosis resembling diabetic glomerulosclerosis. Fewer than 40 cases have been reported. We report a case of HCDD with the novel complication of acquired angioedema.